Brazilian pemphigus [fogo selvagem] - what does this mean
Brazilian pemphigus (fogo selvagem) is an autoimmune skin disorder caused by an abnormal production of antibodies that attack the skin cells, causing painful blisters and lesions on the skin. it is most common in brazil and other south american countries.
What happens during the disease - brazilian pemphigus [fogo selvagem]
Brazilian pemphigus, also known as fogo selvagem, is an autoimmune disorder caused by an igg autoantibody directed against desmoglein 1, a protein that is essential for cell-cell adhesion in the epidermis. this autoantibody binds to desmoglein 1, resulting in a breakdown of the epidermal barrier and the development of painful, itchy blisters. in addition, the autoantibody can also bind to other proteins in the epidermis, leading to further inflammation and damage to the skin.
Treatment and Medical Assistance
Main goal of the treatment: Reduce the severity and frequency of Brazilian pemphigus (fogo selvagem) outbreaks.
- Administering systemic corticosteroids
- Prescribing topical corticosteroids
- Prescribing immunosuppressive drugs
- Prescribing topical calcineurin inhibitors
- Providing photoprotection
- Providing stress management
- Prescribing oral antibiotics
- Providing nutritional support
- Providing lifestyle advice
- Providing physical therapy
15 Days of Hospitalization Required
Average Time for Outpatient Care Not Established
Brazilian pemphigus [fogo selvagem] - Prevention
Brazilian pemphigus [fogo selvagem] can be prevented by avoiding exposure to sunlight, using sunscreen and protective clothing, and avoiding contact with infected individuals. vaccination is also recommended for at-risk individuals and those living in endemic areas.