(L10.3) Brazilian pemphigus [fogo selvagem]

More details coming soon

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190 040 in individuals diagnosis brazilian pemphigus [fogo selvagem] confirmed
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3 763 deaths with diagnosis brazilian pemphigus [fogo selvagem]
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2% mortality rate associated with the disease brazilian pemphigus [fogo selvagem]

Diagnosis brazilian pemphigus [fogo selvagem] is diagnosed Women are 15.67% more likely than Men

80 132

Men receive the diagnosis brazilian pemphigus [fogo selvagem]

1 911 (2.4 %)

Died from this diagnosis.

100
95
90
85
80
75
70
65
60
55
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45
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25
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15
10
5
0
109 908

Women receive the diagnosis brazilian pemphigus [fogo selvagem]

1 852 (1.7 %)

Died from this diagnosis.

Risk Group for the Disease brazilian pemphigus [fogo selvagem] - Men aged 55-59 and Women aged 60-64

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In Men diagnosis is most often set at age 0-1, 5-89
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Less common in men the disease occurs at Age 0-5, 90-95+in in women, the disease manifests at any age
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In Women diagnosis is most often set at age 0-95+

Disease Features brazilian pemphigus [fogo selvagem]

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Absence or low individual and public risk
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Brazilian pemphigus [fogo selvagem] - what does this mean

Brazilian pemphigus (fogo selvagem) is an autoimmune skin disorder caused by an abnormal production of antibodies that attack the skin cells, causing painful blisters and lesions on the skin. it is most common in brazil and other south american countries.

What happens during the disease - brazilian pemphigus [fogo selvagem]

Brazilian pemphigus, also known as fogo selvagem, is an autoimmune disorder caused by an igg autoantibody directed against desmoglein 1, a protein that is essential for cell-cell adhesion in the epidermis. this autoantibody binds to desmoglein 1, resulting in a breakdown of the epidermal barrier and the development of painful, itchy blisters. in addition, the autoantibody can also bind to other proteins in the epidermis, leading to further inflammation and damage to the skin.

Clinical Pattern

More details coming soon

How does a doctor diagnose

  • Physical examination
  • Skin biopsy
  • Serological tests (ELISA, immunofluorescence)
  • Histological analysis
  • Molecular biology tests (PCR, RT-PCR)
  • Immunoblotting

Treatment and Medical Assistance

Main goal of the treatment: Reduce the severity and frequency of Brazilian pemphigus (fogo selvagem) outbreaks.
  • Administering systemic corticosteroids
  • Prescribing topical corticosteroids
  • Prescribing immunosuppressive drugs
  • Prescribing topical calcineurin inhibitors
  • Providing photoprotection
  • Providing stress management
  • Prescribing oral antibiotics
  • Providing nutritional support
  • Providing lifestyle advice
  • Providing physical therapy
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15 Days of Hospitalization Required
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Average Time for Outpatient Care Not Established

Brazilian pemphigus [fogo selvagem] - Prevention

Brazilian pemphigus [fogo selvagem] can be prevented by avoiding exposure to sunlight, using sunscreen and protective clothing, and avoiding contact with infected individuals. vaccination is also recommended for at-risk individuals and those living in endemic areas.